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Article

Open Access

Approach to Patients Suffering from Hydatid Disease in an Endemic Area: Our Experience

Author(s)

Arturo Leonardo Delgado

Full-Text PDF Download XML 89 Views

DOI:10.17265/2328-2150/2026.01.003

Affiliation(s)

Department of Surgery, Walter Sisulu University (WSU) / Nelson Mandela Academic Hospital (NMAH), Umtata, Eastern Cape, South Africa

ABSTRACT

Hydatid disease is one of the most important health problems in developing countries, many of which are endemic for the disease. It can affect any part of the body, commonly lungs and liver. Due to poor data and preventive measures in Sub-Saharan Africa, and other countries, cystic echinococcosis (CE) is regarded as an endemic or prevalent disease. This study aims to evaluate the effectiveness of treatment for children suffering from Hydatid disease. We conducted a retrospective study of children admitted to our Paediatric Surgical Unit with Hydatid disease, particularly Cystic echinococcosis, from May 2016 to January 2025. Variables analysed included age, sex, organs, treatment, complications, and recurrences. Results: Seventy-two children were studied; the age group most affected was 6 to 10 years, accounting for 47%, females accounted for 37%, and males 63%; lungs were affected in 41% of cases the same proportion as the liver; 13% of the patients had cysts in multiple locations. In 48 cases (67%), treatment involved administering anthelmintics for at least a week, followed by PAIR (puncture-aspiration-injection and re-aspiration of the cyst) through an open surgical procedure, with removal of the germinal layer (strongly recommended). Post-operatively, patients received anthelmintics (Albendazole + Praziquantel) for no less than 3 months. In 10 cases (14%), medical treatment alone was sufficient for cyst resolution. No recurrences were documented. Males were more frequently affected, and the liver and lungs were the most commonly affected organs. The absence of documented recurrences suggests that this treatment is suitable in endemic areas.

KEYWORDS

Hydatidosis, PAIR, CE, Echinococus granulosus, Germinal layer.

Cite this paper

Arturo Leonardo Delgado. Approach to Patients Suffering from Hydatid Disease in an Endemic Area: Our Experience. Journal of Pharmacy and Pharmacology 13 (2026) 37-41, doi: 10.17265/2328-2150/2026.01.003

References

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