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Outcome of the Treatment of Hydatid Disease in Children over a Period of 8 Years




Author(s)

Arturo L Delgado, Mfuneko Kopolo, Ernesto Rosales, Anelisa Mnqandi, Chukwuma Joseph Onyeche, Moehketsi Thabane and Yamkela Luke

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DOI:10.17265/2328-2150/2023.06.002

Introduction: Hydatid disease is one of the most important health problems in developing countries. It can affect any part of the human body, commonly affects lungs and liver. Because of poor data and preventive measures in Sub-Saharan Africa, cystic echinococcosis (CE) is regarded as endemic disease. Method: This is a retrospective study of children under 12 years old admitted in paediatric surgical unit at Nelson Mandela Academic Hospital (NMAH), suffering from Cystic echinococcosis from May 2015 to April 2023. We studied groups of age, gender, organs affected, treatment, complications and recurrences. Results: 58 children were studied; the group of age most affected was 5 to 10 years old, 53.4% of females, 48.2% of males, lung hydatid cysts in 43% of cases, same as in the liver; 8.9% of the patients had cysts in multiple locations. In 48 (83%) cases, the treatment was anthelmintics for no less than a week previous the surgical procedure then punction-aspiration-injection and re-aspiration (PAIR), removing the germinal layer (Strongly Recommended), following in the post operatory with anthelmintics no less than 3 months (Albendazole and Praziquantel). In 10 (17%) cases medical treatment was enough for the resolution of the cyst. No documented recurrences. Conclusion: Females were most affected and the liver and lungs were the organs affected with more frequency. No recurrences found, suggesting that this treatment is suitable in endemic areas.

Hydatidosis, PAIR, CE, Echinococcus granulosus, Germinal layer (endocysts).

Delgado, A. F., Kopolo, M., Rosales, E., et al. 2023. "Outcome of the Treatment of Hydatid Disease in Children over a Period of 8 Years." Journal of Pharmacy and Pharmacology 11 (6): 114-121.