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Article
Affiliation(s)

1. Department of Sensory Signaling, Bogomoletz Institute of Physiology National Academy of Sciences of Ukraine, Kyiv 401601, Ukraine
2. International Medical Innovation Center Zepter, Kyiv 02152, Ukraine
3. National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Kyiv 03056, Ukraine

ABSTRACT

In experiments on laboratory animals (n = 100) and in examinations of people (n = 42), the anti-stress effect of low-intensity polychromatic or monochromatic halogen light of the Bioptron device (PILER/PL: 480-3,400 nm, 40 mW/cm2) and LED (light-emitting diode) light of the Medolight-polychrome device (401+467.5+527.5+640.5+940 nm) has been demonstrated objectively. We found out that adult rodents (white mice) showed that 30 min of immobilization stress increased grooming duration by 330%, and after a PL (polarized light) session to acupuncture point (AP) E-36only by 170%-230% compared to the norm. PLs anti-stress effect was determined by its wavelength. Researchers found that red light (the long-wavelength part of the visible light spectrum) had a significantly greater anti-stress effect than green light (medium-wavelength). Red PL application reduced stress-induced grooming by 49.2% and other behavioural responses (sleeping, eating, and physical activity) were partially normalized, while green PL reduced grooming by 31% without affecting other behavioural responses. The short-term immobilization stress weakened the somatic pain response (formalin test) by 28.5% and the visceral one (acetate test) by 26.3%. Red PL has a less pronounced analgesic effect on animals under stress than on animals not under stress. In normal conditions, red PL suppressed somatic pain by 54.4%, visceral pain by 64%, and under stress by 31% and 46.1%, respectively. Under the action of low-intensity LED-light on AP, we have obtained experimental evidence of stress reduction in humans. The latent period for falling asleep in the subjects increased from 393.6 ± 47.1 to 749.3 ± 44.4 s under stress. Applying the Medolight-polychrome device to auricular AP weakened post-stress sleep disturbances: the duration of falling asleep was reduced to 512.5 ± 38.6 s. In persons with daytime stress, the frequency of dreams was 49% ± 5.7%, and after a PL session it was 14.79% ± 5.2%. The results of these studies can be used to develop recommendations for reducing stress in humans.

KEYWORDS

PILER-light, polarized light, Bioptron, LED-light, monochromatic light, polychromatic light, grooming, immobilization stress, analgesia, formalin test, acetate test, acupuncture points, sleep, stress auriculotherapy.

Cite this paper

Journal of US-China Medical Science 19 (2022) 29-45

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