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Antimicrobial Activities of Desert Truffle Extracts and Their Chemical Identification



Author(s)

Dib-Bellahouel S. and Fortas Z.

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DOI:10.17265/2328-2150/2019.11.005

Desert truffles are edible mushrooms and they belong to groupe of ascomycetes. In Algeria, we find them in arid and semiarid area. They are represented by two most genuses: Tirmania (white terfez) and Terfezia (red terfez). The aim of our work is to present extraction technics of the bioactive substances from gleba (ascoms) of Tirmania pinoyi (Maire) Malençon and from the culture filtrate of mycelium of Terfezia claveryi Chatin. Also, we present antifungal and antibacterial activity of these substances in vitro and their identification. There is antifungal activity of different extracts on solid medium, in vitro, against species of Aspergillus, Fusarium, Gliocladium, Candida. Also, there is antibacterial activity against species of Staphylococus, Streptococcus, Bacillus, Enterococcus, Escherichia, and Salmonella. Results show that extracts inhibition varies according to microbial tested species. Bioactive substances of the different extracts were analyzed by GC (gas chromatography)-mass, RMN (Nuclear Magnetic Resonance) and infrared in order to determine the chemical identity. Results show that these substances contain pyrazines and cyclic compounds like quinones.

Desert truffle, antimicrobial activity, bioactive substances, chemical identification.

Dib-Bellahouel, S., et al. 2019. “Antimicrobial Activities of Desert Truffle Extracts and Their Chemical Identification.” Journal of Pharmacy and Pharmacology 7 (11): 593-597.