Affiliation(s)
1. Faculty of Medicine of Tlemcen, Abou bekr Belkaid University of Tlemcen, Tlemcen 13000, Algeria
2. Department of Epidemiology and Preventive Medicine, University Hospital Center of Tlemcen, Tlemcen 13000, Algeria
3. Laboratory Research of Cancer-Cancer Lab No. 30, Abou Bekr Belkaid University of Tlemcen, Tlemcen 13000, Algeria
ABSTRACT
In the world, digestive
cancers represent a major public health problem by their frequency and
severity. Digestive tract cancers are very common malignant
tumors worldwide and are an important cause of cancer-related death. The
objective of our study was to determinate
the survival of digestive cancers in the province of Tlemcen over a period of 5
years. This is a prognostic historical-prospective study with an
exhaustive collection data, which consists of studying the 5-year survival of
digestive cancers in the province of Tlemcen, of all patients with digestive
cancers whatever the stage, diagnosed between 2011 and 2012 and histologically
confirmed in subjects residing in the province of Tlemcen at the moment of
diagnosis. The subjects of our study were identified from the cancer registry
of Tlemcen. In total, 408 cases of digestive cancers were diagnosed over 2
years in Tlemcen province. Most digestive cancers were characterized by a
predominance of men except for cancer of the liver, gallbladder and bile ducts
but whatever the sex, these cancers occur mainly in subjects whose age is
greater than or equal to 45 years. Topographically, for both sexes combined,
the colorectum followed by the stomach were the organs most affected by
digestive cancers. Histopathologically, a predominance of adenocarcinoma has
been noted. The 5-year global survival rate of all digestive cancers was 55.4%,
depending on the localization; colorectal cancer, small bowel cancer,
gallbladder and bile ducts cancer, stomach and esophagus cancers are cancers of
intermediate prognosis whose survival in 5 years is between 40% and 80%. Liver
cancer and pancreatic cancer remain poor prognosis cancers with 5-year survival
rates of 23.08% and 33.3% respectively. The survival of digestive cancers must
be improved by adequate care and surveillance of patients. The prevention of
colorectal cancers which occupy the first place among the digestive cancers is
based essentially on the knowledge of the risk factors and the screening
allowing the improvement of the survival rate. The registry of cancer remains a
fundamental tool of any cancer control program; it constitutes a starting
source for the analysis of survival.
KEYWORDS
Digestive cancers, mortality, survival, prognosis,
register, Tlemcen.
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