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Schiff Bases as Important Class of Pharmacological Agents
Aliaksandr Dzeikala and Anna Sykula
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DOI:10.17265/2328-2150/2018.12.002
Therapeutics are compounds, which do not always exhibit healing powers. They sometimes prevent or control roles. Many compounds, well known or less are treated as the therapeutic agents. Among them, there is a specific group of molecules named commonly as Schiff bases, chemically imines. Schiff bases are aldehyde- or ketone- like compounds in which the carbonyl group is replaced by an imine -HN=СН- or azomethine -NHN=СН- group, they are an important class of compounds for new drug development. Schiff base modifications so far proved to be very effective with increased efficacy and reduced toxicity. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activity. The aim of this work was to present some interesting and promising examples of Schiff bases which exhibit biological activity.
Biological activities, Schiff bases, therapeutic agents.
Dzeikala, A., and Sykula, A. 2018. “Schiff Bases as Important Class of Pharmacological Agents.” Journal of Pharmacy and Pharmacology 6 (12): 989-1009.