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Article
Author(s)
Servet Kefi
Full-Text PDF XML 746 Views
DOI:10.17265/2161-6256/2018.03.001
Affiliation(s)
Department of Genetics and Bioengineering, Kastamonu University, Kastamonu, 37150, Turkey
ABSTRACT
The secondary metabolites synthesized by plants are economically
important chemical compounds in the agricultural and industrial areas such as
food, perfumery and pharmaceutical sectors. In recent years, attempts for their
production by in vitro plant cell and
tissue cultures have been accelerated considerably. Colchicine, the principle
secondary metabolite of Colchicum
autumnale L. and Gloriosa superba L., is an important alkaloid that has poison effect used
for treatment of various diseases and plant breeding
studies. Presently, colchicine has been produced by using the seeds of C. autumnale L. and the tubers of G. superba L. through different chemical extraction methods. Applying in vitro plant cell and tissue cultures
together with metabolic and genetic engineering techniques, large-scale
production of colchicine can be achieved from the above two plant species.
KEYWORDS
Colchicine, plant secondary metabolite, Colchicum autumnale, Gloriosa superba.
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