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Reduction of Nitro Compounds, Through different Reaction Conditions (Combinatory Chemistry)
Lejarazo Gómez Eva F., Santos Santos Elvira and Suarez Torres Sara
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DOI:10.17265/1934-7375/2018.02.004
In this work we intend to approach the study of the chemo-selectivity of a transformation on a polyfunctional compound. An example of how the result of a reaction depends on experimental conditions, different nitrated compounds reduction, will be shown. The reduction reaction was carried out under different conditions found in the literature; they were applied to 1,3-dinitrobenzene and to 4-nitroacetophenone. The reduction conditions were: Zn/NH4Cl, hydrazine and 10% Pd/C, NaBH4 and 10% Pd/C in water, Sn/HCl, NaBH4/ethanol, Na2Sx•9H2O-sulfur (0.2 g to 1.0 g) at different time periods. These reagents preferably affect one of the functional groups present.
Reduction of nitro compounds.
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