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Association of HbA1c Level with Lipid Ratio in Diabetic Patients
Lizete Kļaviņa, Beate Ulmane, Lāsma Milgrāve and GuntaTīcmene
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DOI:10.17265/2328-2150/2018.08.011
Introduction: Diabetes mellitus is a common
disease in the world and the number of diabetes patients is rapidly increasing.
Dyslipidemia is one of the most risk factors for cardiovascular disease which
is more prevalent among adults with diabetes than in the general population. Aim: To
study the correlation of diabetes patients glycated hemoglobin (HbA1c) with
lipid ratios. Materials and methods: Samples were collected from
101 diabetic patients (aged 19-86 years; male 51, female 50). Retrospective
study included data such as age, gender, type of diabetes, HbA1c, total
cholesterol, LDL cholesterol and triglyceride from two family medicine doctor’s
practices. According to the HbA1c level, the patients were divided into three
groups, group A (HbA1c < 7%, n = 58),
group B (7% ≤ HbA1c < 10%, n = 37)
and group C (HbA1c ≥ 10%, n = 6). The correlations of
HbA1c with lipid ratios were analyzed. Results: In the group A the mean
HbA1c was 6.1 ± 0.5%,
mean age—60.6
years, total cholesterol—4.7
mmol/L, LDL—2.8
mmol/L, triglycerides—1.6
mmol/L. In the group B the mean HbA1c was 7.7 ± 0.6%, mean age—64.0
years, total cholesterol—5.7
mmol/L, LDL—3.1
mmol/L, triglycerides—2.2
mmol/L and in the group C the mean HbA1c was 11.2 ± 1.0%, mean age—48.7
years, total cholesterol—4.9
mmol/L, LDL—2.7
mmol/L, triglycerides—1.7
mmol/L. Conclusions: From all groups highest total
cholesterol, LDL cholesterol, triglycerides were patients in the group B. In
others two groups lipid profile changes were without any significant
differences and there was no association with HbA1c.
Diabetes, HbA1c, total cholesterol, LDL cholesterol, triglycerides.
Kļaviņa, L., et al. 2018. “Association of HbA1c Level with Lipid Ratio in Diabetic Patients.” Journal of Pharmacy and Pharmacology 6 (8): 796-799.