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Hematopoietic Stem Cell Transplantation in Vietnam: Current Status and Future Directions
Phu Duc Vinh Huynh, Man Van Huynh, Nam Duy Hoang, Ngon Thien Huynh, Tuan Xuan Ma, Thu Hanh Nguyen, Dung Chi Phu and Binh Tan Nguyen
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DOI:10.17265/2328-2150/2018.08.007
In recent years, there have been an increasing
number of hematologic patients in Vietnam. Hematopoietic stem cell
transplantation (HSCT) is fast becoming an effective method to cure many benign
and malignant blood disorders. Nine transplant centers are operating throughout
Vietnam. HCMC Blood Transfusion Hematology Hospital (BTH) is one of these
centers where bone marrow, peripheral blood and cord blood stem cell
transplantation were first conducted in our country. At BTH, half of the
patients received allogeneic HSCT, mainly from matched sibling donors due to
lack of a national bone marrow donor registry. While acute myeloid leukemia was
a common indication of allogeneic HSCT, most of the patients undergoing
autologous HSCT had multiple myeloma. One major issue we encountered concerned
bacterial and fungal infections during neutropenia period. Because of an
endemic area, CMV reactivation
frequently occurred. Five-year overall survival (OS)
and event-free survival (EFS)
were 47% and 46%, respectively. To create more
opportunities for patients, our future directions will focus on some new
transplant procedures, such as haploidentical, unrelated and cord blood
transplantation.
HSCT, Vietnam, BTH, allogeneic, autologous.
Huynh, P. D. V., et al. 2018. “Hematopoietic Stem Cell Transplantation in Vietnam: Current Status and Future Directions.” Journal of Pharmacy and Pharmacology 6 (8): 765-771.