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Double Problem—Clostridium difficile and Diabetes



Author(s)

Ioana Florina Iordan and Carmen Manciuc

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DOI:10.17265/2328-2150/2018.02.010

Considered to be the most common cause of nosocomial diarrhea, Clostridium difficile infection is a daily clinical reality, and its incidence is increasing globally. Many factors have been implicated in causing this infection, including glucose metabolism disorder. Aim: to evaluate the prevalence of diabetes among patients with C. difficile colitis and assessing the risk of disease relapse and extension of the disease, in combination with diabetes mellitus infection. Materials and methods: were included in the study 102 patients known to have diabetes type 1 or type 2 admitted to our clinic between January 2016 and June 2017, from a total of 648 patients diagnosed with C. difficile colitis. We used data from observation charts of patients. Results: 98% were suffering from type 2 diabetes, mostly female, respectively from urban areas, 29.4% being at the second hospitalization in our clinic for the same symptoms. Studying the average length of hospitalization, compared with a control group, we noticed the prolongation of hospitalization for patients with metabolic pathology associated with approximately 7 days. Conclusions: Diabetes is a risk factor for the occurrence and recurrence of C. difficile infection, an additional risk factor being the age.

Clostridium difficile, diabetes, multidisciplinary approach, risk factor.

Iordan, I. F., and Manciuc, C. 2018. “Double Problem—Clostridium difficile and Diabetes.” Journal of Pharmacy and Pharmacology 6 (2): 170-174.