Affiliation(s)
1. Institute of Computer Science and Engineering, National Chiao Tung University, Hsinchu, Taiwan, R.O.C.
2. Institute of Biomedical Engineering, National Chiao Tung University, Hsinchu, Taiwan, R.O.C.
3. A-Neuron Electronic Corporation, Hsinchu, Taiwan, R.O.C.
4. Yo-Yo Pediatric Clinic, Kaohsiung, Taiwan, R.O.C.
5. Department of Computer Science, National Chiao Tung University, Hsinchu, Taiwan, R.O.C.
ABSTRACT
HRV (heart rate
variability) is a general noninvasive method for indicating the activities of
ANS (autonomic nervous
system). The surrogate of HRV is PRV (pulse rate variability), where the variability of
resting PPG (photo plethysmo graphy) indicates the
activities of ANS and peripheral circulation. However, the quick responses of
thermoregulation and limb movement are restrictedly performed since of the
beat-to-beat timescale property of PRV. Recently, iPRV
(instantaneous pulse rate variability) has been
developed to break the limitation. The iPRV adopts empirical mode decomposition
for noise reduction and estimates the instantaneous period for higher time resolution.
Thus, an ultra-frequency band called VHF
(very high frequency) was held. The aim of this study
is to concentrate the iPRV presentation on fever adolescent who is possibly
under immature body regulation. Thirty participates, whose age were 7 to 18 years
old, were recruited in pediatric clinic. The resting PPG signals were acquired
for 10 minutes in a supine position. The analysis results show the conventional
ranges of iPRV also observe the activities of ANS. As well, the modified
indices including VHF are significant difference (p-value < 0.05) between fever and feverless symptoms. Based on
the statistical evidence, this study provides the potential of the indicator of
thermoregulation on peripheral circulation.
KEYWORDS
Peripheral circulation, instantaneous
pulse rate variability, very high frequency band.
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