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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
B. Angelovska, S. Maleska-Stojadinovikj, E. Drakalska and B. Gjorgjeska
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DOI:10.17265/2328-2150/2017.05.003
Antirheumatic and analgesics drugs are the most commonly prescribed medications for treatment of acute and chronic pain. Frequent application of these agents often causes adverse effects. So, in order to avoid the incidence of side effects, topical analgesics are treatment of choice for localized muscle pain. Topical analgesics offer the potential to provide the same analgesic relief provided by oral analgesics but with minimal adverse systemic effects. The aim of this study is to present the preparation and characterization of topical analgesic gel named “Russian water”. Gel is composed of Menthol, Benzocaine, Procaine HCl as topical analgesic agents indicated for temporary relief of pain. Obtained results showed prolonged analgesic effect compared with liquid ethanol solution composed of the same components.
Pain, gel, Russian water, antirheumatic, analgesic.
Angelovska, B., et al. 2017. “Production of Gel with Menthol, Benzocaine and Procaine HCl for Topical Application in Rheumatoid Arthritis Patients.” Journal of Pharmacy and Pharmacology 5 (5): 245-248.