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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Article
Pancreatic Cancer with Normal CA 19-9 and Lewis Antigen Negative—Case Report
Author(s)
Rodrigo Coutinho Mariano, Noam Fabel Ponde, Daniel Eiger, Patricia Taranto, Vanderlei Segatelli, Daniela Pezzutti Armentano and Rene Claudio Gansl
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DOI:10.17265/2328-2150/2017.03.005
Affiliation(s)
ABSTRACT
Pancreatic cancer is an aggressive
and lethal disease that affects especially older population. Its more relevant
tumor marker is CA 19-9 (carbohydrate
antigen 19-9), although it can be elevated in others clinical situations, like
cholangitis and cholestasis. Otherwise, a small people subset, like our
patient, do not produce this tumor marker, as on blood as in the tumor, because
they are incapable to express the Lewis Antigen. Therefore, this case report is
about a patient without Lewis Antigen express and CA 19-9 low levels. We will
report a rapid disease progression, despite of low CA 19-9, comparing with available data that often show better prognosis in
this setting. Conclusion: Low
levels of CA 19-9 do not predict good response or better prognosis in patients
that do not express Lewis
Antigen.
KEYWORDS
Pancreatic cancer, CA 19-9, Lewis Antigen, prognosis.
Cite this paper
Mariano, R. C., et al. 2017. “Pancreatic Cancer with Normal CA 19-9 and Lewis Antigen Negative—Case Report.” Journal of Pharmacy and Pharmacology 5 (3): 149-152.
References