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Article
Author(s)
Khilko Tatiana Dmytrivna, Yakubtsova Irina Volodymyrivna*, Konopelnyuk Victoria Vasylivna, Preobrazhenska Tamara Dmytrivna, Kot Larisa Ivanivna and Ostapchenko Lyudmila Ivanivna
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DOI:10.17265/2161-6213/2016.3-4.006
Affiliation(s)
Educational and Scientific Centre “Institute of Biology”, Taras Shevchenko Kyiv National University, Kyiv 01601, Ukraine
ABSTRACT
Comparative evaluation of blood lipids content and lipid composition of cytosol membranes and plasma membrane of hepatocytes were carried out in the normal and under conditions of high calorie diet fed rats. It was shown corrective effect powder seeds Trigonella foenum graecum L. on the lipid composition of blood serum of rats with obesity, lowering TG (24.6%), LDL (25%), VLDL (23.8%), cholesterol (16%) and increased HDL levels (25.4%). Our experimental data indicate that feeding the animals high calorie diet supplemented with fine powder fenugreek affect the lipid composition of blood and liver cells, by directing the values of indicators to the levels of the control animals: increase of 70% phosphatidylcholine, 60% phosphatidylinositol and phosphatidylethanolamine, decrease to 56.5% content of sphingomyelin compared to a group of experimental obese rats. Our results allows us to consider Trigonella foenum graecum L. as a possible remedy for the prevention of obesity.
KEYWORDS
High calorie diet, blood lipids, hepatocytes membranes lipid composition, Trigonella foenum graecum L.
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