Paper Status Tracking

Journals by Title

Journals by Subject

Contact us

	[email protected]
	3275638434

	Paper Publishing WeChat

Useful Links

Creative Commons Attribution-NonCommercial 4.0 International License

Article

Open Access

Effect of Avocado (Persea Americana), Cabbage (Brassica Oleracea) and Ginger (Zingiber Officinale) on Rat Liver and Thyroid Injuries Induced by CCl4 (Carbon Tetrachloride)

Author(s)

Asmaa F. Hamouda, Manal Y. Sameeh and Randa M. Shrourou

Full-Text PDF Download XML 2056 Views

DOI:10.17265/2328-2150/2016.03.002

Affiliation(s)

ABSTRACT

Avocado, Cabbage, and Ginger are a part of a regular human diet and have antioxidant, and antitumor effects. The effect of AVOE (avocado), GE (Ginger) and CE (Cabbage) extracts separately on liver NO (nitric oxide), MDA (malondialdehyde), as well as serum AST (aspartate aminotransferase), ALT (alanine aminotransferase), total bilirubin, TC (total cholesterol), T.G (triglyceride), HDL cholesterol (high-density lipoprotein), LDL cholesterol (low-density lipoprotein), TSH (thyroid-stimulating hormone), T3 (Triiodothyronine), T4 (Thyroxine) in rats treated and untreated with CCl4 (carbon tetrachloride) was studied. The levels of NO, MDA, as well as serum AST, ALT, total bilirubin, TC, T.G, LDL, and TSH, showed an elevation while, HDL, T3 and T4 showed the decline in rats treated with CCl4 as compared to control. Treatment of rats with AVOE and GE pre, during, and post CCl4 administration improve NO, MDA, as well as serum AST, ALT, total bilirubin, TC, T.G, HDL, LDL, TSH, T3, T4 as compared to CCl4. Treatment of rats with CE pre, during, and post CCl4 administration did not improve in the thyroid hormones and lipid profile levels as compared to CCl4. These findings suggest that avocado and ginger treatment exerts a protective effect on metabolic disorders by decreasing oxidative stress.

KEYWORDS

Liver injuries, CCl4 (carbon tetrachloride), avocado (Persea Americana), cabbage (Brassica Oleracea) and ginger (Zingiber Officinale), thyroid function.

Cite this paper

Asmaa F. Hamouda., et al. 2016. “Effect of Avocado (Persea Americana), Cabbage (Brassica Oleracea) and Ginger (Zingiber Officinale) on Rat Liver and Thyroid Injuries Induced by CCl4 (Carbon Tetrachloride).” Journal of Pharmacy and Pharmacology 4 (3): 108-118.

References